Yes, there was that episode when he merged with lex luthor and was literally ripped off of lex by the flash. And on the last epsiode when he merged with darkseid and lex luthor had to send him to the source wall.

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One Response to “Has Brainiac From The Justice League Unlimited Ever Been Defeat By Superman Or Anyone Else?”
  1. No, in the last episode he takes over the world, and destroys it That’s the last episode.

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